› 3iuf

X-ray diffraction
1.8Å resolution

Crystal structure of the C2H2-type zinc finger domain of human ubi-d4

Released:
DOI: 10.2210/pdb3iuf/pdb
PDB entry 3iuf coloured by chain, front view.
PDB entry 3iuf coloured by chain, side view.
PDB entry 3iuf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the Cys2His2-type zinc finger domain of human DPF2.
Zhang W, Xu C, Bian C, Tempel W, Crombet L, MacKenzie F, Min J, Liu Z, Qi C
Biochem Biophys Res Commun 413 58-61 (2011)
PMID: 21888896

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187749 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger protein ubi-d4 Chain: A
Molecule details ›
Chain: A
Length: 48 amino acids
Theoretical weight: 5.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q92785 (Residues: 203-249; Coverage: 12%)
Gene names: BAF45D, DPF2, REQ, UBID4

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21212
Unit cell:
a: 24.714Å b: 57.657Å c: 22.585Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.193 0.237
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Micronutrient (Zn, Cu, Fe)-gene interactions in ageing and inflammatory age-related diseases: implications for treatments.
Mocchegiani et al. (2012)
2 more

3 mentions without citation

A novel GLI3 mutation affecting the zinc finger domain leads to preaxial-postaxial polydactyly-syndactyly complex.
Volodarsky et al. (2014)
2 more