3ixx

Electron Microscopy
15Å resolution

The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53

Released:

Function and Biology Details

Reactions catalysed:
Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero 600-mer (preferred)
PDBe Complex ID:
PDB-CPX-207606 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Envelope protein E Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 400 amino acids
Theoretical weight: 43.27 KDa
Source organism: West Nile virus
Expression system: Not provided
UniProt:
  • Canonical: A7TZT4 (Residues: 291-690; Coverage: 12%)
Sequence domains:
Peptide pr Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 80 amino acids
Theoretical weight: 8.74 KDa
Source organism: West Nile virus
Expression system: Not provided
UniProt:
  • Canonical: Q3I100 (Residues: 126-205; Coverage: 2%)
Sequence domains: Flavivirus polyprotein propeptide
E53 Fab Fragment (chain H) Chains: G, I
Molecule details ›
Chains: G, I
Length: 221 amino acids
Theoretical weight: 23.63 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
E53 Fab Fragment (chain L) Chains: H, J
Molecule details ›
Chains: H, J
Length: 215 amino acids
Theoretical weight: 23.59 KDa
Source organism: Mus musculus
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 15Å
Relevant EMDB volumes: EMD-5103
Expression systems:
  • Not provided
  • Escherichia coli