› 3j2i

Electron Microscopy
11.9Å resolution

Structure of late pre-60S ribosomal subunits with nuclear export factor Arx1 bound at the peptide exit tunnel

Released:
DOI: 10.2210/pdb3j2i/pdb
PDB entry 3j2i coloured by chain, front view.
PDB entry 3j2i coloured by chain, side view.
PDB entry 3j2i coloured by chain, top view.
Source organisms:
Primary publication:
Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel.
Bradatsch B, Leidig C, Granneman S, Gnädig M, Tollervey D, Böttcher B, Beckmann R, Hurt E
Nat Struct Mol Biol 19 1234-41 (2012)
PMID: 23142978
Related structures: EMD-5513

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194061 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Eukaryotic translation initiation factor 6 Chain: B
Molecule details ›
Chain: B
Length: 245 amino acids
Theoretical weight: 26.48 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q12522 (Residues: 1-245; Coverage: 100%)
Gene names: CDC95, LPZ15C, TIF6, YPR016C
Sequence domains: eIF-6 family
Proliferation-associated protein 2G4 Chain: A
Molecule details ›
Chain: A
Length: 394 amino acids
Theoretical weight: 43.85 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9UQ80 (Residues: 1-394; Coverage: 100%)
Gene names: EBP1, PA2G4
Sequence domains: Metallopeptidase family M24

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 11.9Å
Relevant EMDB volumes: EMD-5513

Quick links

Citations

20 review citations

Ribosome biogenesis in the yeast Saccharomyces cerevisiae.
Woolford et al. (2013)
19 more

1 mention without citation

Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel.
Bradatsch et al. (2012)