› 3j3z

Electron Microscopy
23.4Å resolution

Structure of MA28-7 neutralizing antibody Fab fragment from electron cryo-microscopy of enterovirus 71 complexed with a Fab fragment

Released:
DOI: 10.2210/pdb3j3z/pdb
PDB entry 3j3z coloured by chain, front view.
PDB entry 3j3z coloured by chain, side view.
PDB entry 3j3z coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody.
Lee H, Cifuente JO, Ashley RE, Conway JF, Makhov AM, Tano Y, Shimizu H, Nishimura Y, Hafenstein S
J Virol 87 11363-70 (2013)
PMID: 23946455
Related structures: EMD-5673

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213304 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
MA28-7 neutralizing antibody light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.26 KDa
Source organism: Mus musculus
MA28-7 neutralizing antibody heavy chain Chain: H
Molecule details ›
Chain: H
Length: 220 amino acids
Theoretical weight: 23.35 KDa
Source organism: Mus musculus

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 23.4Å
Relevant EMDB volumes: EMD-5673

Quick links

Citations

9 review citations

Recent Progress towards Novel EV71 Anti-Therapeutics and Vaccines.
Ng et al. (2015)
8 more

1 mention without citation

A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody.
Lee et al. (2013)