› 3j9j

Electron Microscopy
3.28Å resolution

Structure of the capsaicin receptor, TRPV1, determined by single particle electron cryo-microscopy

Released:
DOI: 10.2210/pdb3j9j/pdb
PDB entry 3j9j coloured by chain, front view.
PDB entry 3j9j coloured by chain, side view.
PDB entry 3j9j coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.
Barad BA, Echols N, Wang RY, Cheng Y, DiMaio F, Adams PD, Fraser JS
Nat Methods 12 943-6 (2015)
PMID: 26280328
Related structures: EMD-5778

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128685 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transient receptor potential cation channel subfamily V member 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 586 amino acids
Theoretical weight: 67.23 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: O35433 (Residues: 111-719; Coverage: 70%)
Gene names: Trpv1, Vr1, Vr1l
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.275Å
Relevant EMDB volumes: EMD-5778
Expression system: Homo sapiens

Quick links

Citations

16 review citations

Dawning of a new era in TRP channel structural biology by cryo-electron microscopy.
Madej et al. (2018)
15 more

14 mentions without citation

Thermosensory Transient Receptor Potential Ion Channels and Asthma.
Kytikova et al. (2021)
13 more