› 3jqh

X-ray diffraction
2.2Å resolution

Structure of the neck region of the glycan-binding receptor DC-SIGNR

Released:
DOI: 10.2210/pdb3jqh/pdb
PDB entry 3jqh coloured by chain, front view.
PDB entry 3jqh coloured by chain, side view.
PDB entry 3jqh coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Segmented helical structure of the neck region of the glycan-binding receptor DC-SIGNR.
Feinberg H, Tso CK, Taylor ME, Drickamer K, Weis WI
J Mol Biol 394 613-20 (2009)
PMID: 19835887

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190560 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-type lectin domain family 4 member M Chain: A
Molecule details ›
Chain: A
Length: 167 amino acids
Theoretical weight: 19.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H2X3 (Residues: 101-264; Coverage: 41%)
Gene names: CD209L, CD209L1, CD299, CLEC4M

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P4212
Unit cell:
a: 34.17Å b: 34.17Å c: 36.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.194 0.216
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Recent insights into structures and functions of C-type lectins in the immune system.
Drickamer et al. (2015)
4 more

5 mentions without citation

The structural basis of accelerated host cell entry by SARS-CoV-2†.
Seyran et al. (2021)
4 more