› 3jrk

X-ray diffraction
1.97Å resolution

A putative tagatose 1,6-diphosphate aldolase from Streptococcus pyogenes

Released:
DOI: 10.2210/pdb3jrk/pdb
PDB entry 3jrk coloured by chain, front view.
PDB entry 3jrk coloured by chain, side view.
PDB entry 3jrk coloured by chain, top view.
Source organism: Streptococcus pyogenes serotype M1
Entry authors: Fan Y, Volkart L, Clancy S, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Reaction catalysed: 
D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159110 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tagatose 1,6-diphosphate aldolase 2 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 322 amino acids
Theoretical weight: 36.34 KDa
Source organism: Streptococcus pyogenes serotype M1
Expression system: Escherichia coli
UniProt:
  • Canonical: P63705 (Residues: 6-327; Coverage: 99%)
Gene names: M5005_Spy1635, SPy_1919, lacD.2, lacD2
Sequence domains: DeoC/LacD family aldolase
Structure domains: Aldolase class I

Ligands and Environments

1 bound ligand:
Ligand GOL 9 x GOL
1 modified residue:
Ligand MSE 48 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 53.517Å b: 169.729Å c: 167.054Å
α: 90° β: 94.09° γ: 90°
R-values:
R R work R free
0.19 0.188 0.23
Expression system: Escherichia coli

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