› 3k3f

X-ray diffraction
2.3Å resolution

Crystal Structure of the Urea Transporter from Desulfovibrio Vulgaris

Released:
DOI: 10.2210/pdb3k3f/pdb
PDB entry 3k3f coloured by chain, front view.
PDB entry 3k3f coloured by chain, side view.
PDB entry 3k3f coloured by chain, top view.
Source organism: Desulfovibrio vulgaris str. Hildenborough
Primary publication:
Crystal structure of a bacterial homologue of the kidney urea transporter.
Levin EJ, Quick M, Zhou M
Nature 462 757-61 (2009)
PMID: 19865084

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180790 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Urea transporter DVU1160 Chain: A
Molecule details ›
Chain: A
Length: 340 amino acids
Theoretical weight: 36.01 KDa
Source organism: Desulfovibrio vulgaris str. Hildenborough
Expression system: Escherichia coli
UniProt:
  • Canonical: Q72CX3 (Residues: 2-337; Coverage: 100%)
Gene name: DVU_1160
Sequence domains: Urea transporter
Structure domains: Ammonium transporter AmtB like domains

Ligands and Environments

1 bound ligand:
Ligand AU 9 x AU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P63
Unit cell:
a: 110.131Å b: 110.131Å c: 84.861Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.18 0.179 0.204
Expression system: Escherichia coli

Quick links

Citations

15 review citations

The ABCs of membrane transporters in health and disease (SLC series): introduction.
Hediger et al. (2013)
14 more

8 mentions without citation

Water in Nanopores and Biological Channels: A Molecular Simulation Perspective.
Lynch et al. (2020)
7 more