› 3k7b

X-ray diffraction
2.1Å resolution

The structure of the poxvirus A33 protein reveals a dimer of unique C-type lectin-like domains.

Released:
DOI: 10.2210/pdb3k7b/pdb
PDB entry 3k7b coloured by chain, front view.
PDB entry 3k7b coloured by chain, side view.
PDB entry 3k7b coloured by chain, top view.
Source organism: Vaccinia virus WR
Primary publication:
The structure of the poxvirus A33 protein reveals a dimer of unique C-type lectin-like domains.
Su HP, Singh K, Gittis AG, Garboczi DN
J Virol 84 2502-10 (2010)
PMID: 20032175

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159488 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein OPG161 Chains: A, B
Molecule details ›
Chains: A, B
Length: 96 amino acids
Theoretical weight: 11.06 KDa
Source organism: Vaccinia virus WR
Expression system: Escherichia coli
UniProt:
  • Canonical: P68617 (Residues: 90-185; Coverage: 52%)
Gene names: A33R, OPG161, VACWR156
Sequence domains: Chordopoxvirus A33R protein
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: C2
Unit cell:
a: 80.94Å b: 56.32Å c: 41.68Å
α: 90° β: 110.68° γ: 90°
R-values:
R R work R free
0.218 0.218 0.257
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Membrane fusion during poxvirus entry.
Moss B. (2016)
1 more

6 mentions without citation

Immunogenic proteins and potential delivery platforms for mpox virus vaccine development: A rapid review.
Wang et al. (2023)
5 more