Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180234 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Processed angiotensin-converting enzyme 2
Molecule details ›
Chains: A, B, C, D
Length: 597 amino acids
Theoretical weight: 69.15 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Angiotensin-converting enzyme
Length: 597 amino acids
Theoretical weight: 69.15 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q9BYF1 (Residues: 19-615; Coverage: 76%)
Sequence domains: Angiotensin-converting enzyme
Spike glycoprotein
Molecule details ›
Chains: E, F, G, H
Length: 136 amino acids
Theoretical weight: 15.03 KDa
Source organism: Human coronavirus NL63
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Coronavirus spike glycoprotein S1
Structure domains: Immunoglobulin-like
Length: 136 amino acids
Theoretical weight: 15.03 KDa
Source organism: Human coronavirus NL63
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q6Q1S2 (Residues: 481-616; Coverage: 10%)
Sequence domains: Coronavirus spike glycoprotein S1
Structure domains: Immunoglobulin-like
