› 3kt7

X-ray diffraction
1.77Å resolution

Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complex

Released:
DOI: 10.2210/pdb3kt7/pdb
Model geometry
Fit model/data
PDB entry 3kt7 coloured by chain, front view.
PDB entry 3kt7 coloured by chain, side view.
PDB entry 3kt7 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complex.
Kim HS, Kim HL, Kim KH, Kim DJ, Lee SJ, Yoon JY, Yoon HJ, Lee HY, Park SB, Kim SJ, Lee JY, Suh SW
OpenAccess logo Nucleic Acids Res 38 2099-110 (2010)
PMID: 20040577

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154007 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prolyl 3,4-dihydroxylase TPA1 Chain: A
Molecule details ›
Chain: A
Length: 633 amino acids
Theoretical weight: 73.02 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P40032 (Residues: 21-644; Coverage: 97%)
Gene names: TPA1, YER049W
Sequence domains: Oxoglutarate and iron-dependent oxygenase degradation C-term
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand FE 1 x FE
Ligand AKG 1 x AKG
Ligand SO4 4 x SO4
Ligand GOL 1 x GOL
1 modified residue:
Ligand LVN 1 x LVN

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P321
Unit cell:
a: 136.293Å b: 136.293Å c: 79.832Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.18 0.179 0.205
Expression system: Escherichia coli

Quick links

Citations

4 review citations

RNA degradation in Saccharomyces cerevisae.
Parker R. (2012)
3 more

4 mentions without citation

Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy.
Loenarz et al. (2014)
3 more