› 3kvh

X-ray diffraction
1.7Å resolution

Crystal structure of human protein syndesmos (NUDT16-like protein)

Released:
DOI: 10.2210/pdb3kvh/pdb
PDB entry 3kvh coloured by chain, front view.
PDB entry 3kvh coloured by chain, side view.
PDB entry 3kvh coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tresaugues L, Siponen MI, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson A, Johansson I, Kallas A, Karlberg T, Kotenyova T, Kotzsch A, Kraulis P, Moche M, Nielsen TK, Nyman T, Persson C, Roos AK, Schuler H, Schutz P, Thorsell AG, Van Den Berg S, Weigelt J, Welin M, Wisniewska M, Nordlund P, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189688 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tudor-interacting repair regulator protein Chain: A
Molecule details ›
Chain: A
Length: 214 amino acids
Theoretical weight: 23.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BRJ7 (Residues: 6-211; Coverage: 98%)
Gene names: NUDT16L1, SDOS, TIRR
Structure domains: Nucleoside Triphosphate Pyrophosphohydrolase

Ligands and Environments

2 bound ligands:
Ligand GOL 1 x GOL
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-3
Spacegroup: C2
Unit cell:
a: 68.811Å b: 60.278Å c: 60.483Å
α: 90° β: 118.64° γ: 90°
R-values:
R R work R free
0.185 0.184 0.217
Expression system: Escherichia coli

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