› 3lbs

X-ray diffraction
2.15Å resolution

Crystal structure of the cytoplasmic tail of (pro)renin receptor as a MBP fusion (Maltose-bound form)

Released:
DOI: 10.2210/pdb3lbs/pdb
PDB entry 3lbs coloured by chain, front view.
PDB entry 3lbs coloured by chain, side view.
PDB entry 3lbs coloured by chain, top view.
Source organisms:
Primary publication:
Structural analysis of the intracellular domain of (pro)renin receptor fused to maltose-binding protein.
Zhang Y, Gao X, Michael Garavito R
Biochem Biophys Res Commun 407 674-9 (2011)
PMID: 21420935

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131118 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Maltose/maltodextrin-binding periplasmic protein; Renin receptor C-terminal fragment Chains: A, B
Molecule details ›
Chains: A, B
Length: 384 amino acids
Theoretical weight: 42.41 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0AEX9 (Residues: 29-390; Coverage: 98%)
  • Canonical: O75787 (Residues: 333-350; Coverage: 5%)
Gene names: ATP6AP2, ATP6IP2, CAPER, ELDF10, HT028, JW3994, MSTP009, PSEC0072, b4034, malE
Sequence domains: Bacterial extracellular solute-binding protein
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P212121
Unit cell:
a: 41.949Å b: 96.784Å c: 191.45Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.212 0.278
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

The (pro)renin receptor. A decade of research: what have we learned?
Krop et al. (2013)
5 more

5 mentions without citation

Crystal structures of MBP fusion proteins.
Waugh DS. (2016)
4 more