› 3lh9

X-ray diffraction
2.4Å resolution

Crystal structure of mouse VPS26B(L197S/R199E) in spacegroup P41 21 2

Released:
DOI: 10.2210/pdb3lh9/pdb
PDB entry 3lh9 coloured by chain, front view.
PDB entry 3lh9 coloured by chain, side view.
PDB entry 3lh9 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Assembly and solution structure of the core retromer protein complex.
Norwood SJ, Shaw DJ, Cowieson NP, Owen DJ, Teasdale RD, Collins BM
Traffic 12 56-71 (2011)
PMID: 20875039

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183926 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vacuolar protein sorting-associated protein 26B Chains: A, B
Molecule details ›
Chains: A, B
Length: 340 amino acids
Theoretical weight: 39.65 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8C0E2 (Residues: 7-336; Coverage: 98%)
Gene name: Vps26b
Sequence domains: Vacuolar protein sorting-associated protein 26
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P41212
Unit cell:
a: 118.35Å b: 118.35Å c: 214.513Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.199 0.228
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Retromer: a master conductor of endosome sorting.
Burd et al. (2014)
14 more