› 3lk5

X-ray diffraction
1.9Å resolution

Crystal structure of putative Geranylgeranyl pyrophosphate synthase from Corynebacterium glutamicum

Released:
DOI: 10.2210/pdb3lk5/pdb
PDB entry 3lk5 coloured by chain, front view.
PDB entry 3lk5 coloured by chain, side view.
PDB entry 3lk5 coloured by chain, top view.
Source organism: Corynebacterium glutamicum
Entry authors: Malashkevich VN, Toro R, Patskovsky Y, Sauder JM, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
Prenyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185617 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Geranylgeranyl pyrophosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 380 amino acids
Theoretical weight: 41.48 KDa
Source organism: Corynebacterium glutamicum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8NNM1 (Residues: 3-370; Coverage: 99%)
Gene name: Cgl2172
Sequence domains: Polyprenyl synthetase
Structure domains: Farnesyl Diphosphate Synthase

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P3121
Unit cell:
a: 125.434Å b: 125.434Å c: 52.067Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.17 0.168 0.198
Expression system: Escherichia coli BL21(DE3)

Quick links