› 3llk

X-ray diffraction
2Å resolution

Sulfhydryl Oxidase Fragment of Human QSOX1

Released:
DOI: 10.2210/pdb3llk/pdb
PDB entry 3llk coloured by chain, front view.
PDB entry 3llk coloured by chain, side view.
PDB entry 3llk coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
QSOX contains a pseudo-dimer of functional and degenerate sulfhydryl oxidase domains.
Alon A, Heckler EJ, Thorpe C, Fass D
FEBS Lett 584 1521-5 (2010)
PMID: 20211621

Function and Biology Details

Reaction catalysed: 
2 R'C(R)SH + O(2) = R'C(R)S-S(R)CR' + H(2)O(2)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126252 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sulfhydryl oxidase 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 261 amino acids
Theoretical weight: 29.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00391 (Residues: 286-546; Coverage: 36%)
Gene names: QSCN6, QSOX1, UNQ2520/PRO6013
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand FAD 3 x FAD
1 bound ligand:
Ligand FLC 1 x FLC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: C222
Unit cell:
a: 83.481Å b: 161.573Å c: 121.94Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.237 0.272
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Structure, mechanism, and evolution of Ero1 family enzymes.
Araki et al. (2012)
9 more

3 mentions without citation

The dynamic disulphide relay of quiescin sulphydryl oxidase.
Alon et al. (2012)
2 more