Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
homo trimer (preferred)
Assembly name:
TNF receptor-associated factor 2 (preferred)
PDBe Complex ID:
PDB-CPX-171450 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TNF receptor-associated factor 2
Molecule details ›
Chains: A, B, C, D, E, F
Length: 72 amino acids
Theoretical weight: 8.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: TNF receptor-associated factor BIRC3 binding domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 72 amino acids
Theoretical weight: 8.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q12933 (Residues: 266-329; Coverage: 13%)
Sequence domains: TNF receptor-associated factor BIRC3 binding domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X29A
Spacegroup:
R3
Expression system: Escherichia coli
