Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-171449 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
TNF receptor-associated factor 2
Molecule details ›
Chains: A, B
Length: 66 amino acids
Theoretical weight: 7.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: TNF receptor-associated factor BIRC3 binding domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 66 amino acids
Theoretical weight: 7.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q12933 (Residues: 266-329; Coverage: 13%)
Sequence domains: TNF receptor-associated factor BIRC3 binding domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
TNF receptor-associated factor 1
Molecule details ›
Chain: C
Length: 65 amino acids
Theoretical weight: 7.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: TNF receptor-associated factor BIRC3 binding domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 65 amino acids
Theoretical weight: 7.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q13077 (Residues: 181-244; Coverage: 15%)
Sequence domains: TNF receptor-associated factor BIRC3 binding domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Baculoviral IAP repeat-containing protein 3
Molecule details ›
Chain: D
Length: 75 amino acids
Theoretical weight: 8.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Inhibitor of Apoptosis domain
Structure domains: Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Length: 75 amino acids
Theoretical weight: 8.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q13489 (Residues: 26-99; Coverage: 12%)
Sequence domains: Inhibitor of Apoptosis domain
Structure domains: Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
