› 3m5b

X-ray diffraction
2Å resolution

Crystal structure of the BTB domain from FAZF/ZBTB32

Released:
DOI: 10.2210/pdb3m5b/pdb
PDB entry 3m5b coloured by chain, front view.
PDB entry 3m5b coloured by chain, side view.
PDB entry 3m5b coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Insights into strand exchange in BTB domain dimers from the crystal structures of FAZF and Miz1.
Stogios PJ, Cuesta-Seijo JA, Chen L, Pomroy NC, Privé GG
J Mol Biol 400 983-97 (2010)
PMID: 20493880

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195173 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger and BTB domain-containing protein 32 Chains: A, B
Molecule details ›
Chains: A, B
Length: 119 amino acids
Theoretical weight: 12.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y2Y4 (Residues: 1-117; Coverage: 24%)
Gene names: FAZF, TZFP, ZBTB32, ZNF538
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P2
Unit cell:
a: 49.076Å b: 32.809Å c: 69.425Å
α: 90° β: 108.2° γ: 90°
R-values:
R R work R free
0.189 0.186 0.244
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Regulation of hematopoietic development by ZBTB transcription factors.
Maeda T. (2016)
12 other articles

2 mentions without citation

Analysis of dimerization of BTB-IVR domains of Keap1 and its interaction with Cul3, by molecular modeling.
Chauhan et al. (2013)
1 more