› 3mdb

X-ray diffraction
2.95Å resolution

Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4

Released:
DOI: 10.2210/pdb3mdb/pdb
PDB entry 3mdb coloured by chain, front view.
PDB entry 3mdb coloured by chain, side view.
PDB entry 3mdb coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Shen L, Tong Y, Tempel W, MacKenzie F, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131098 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Kinesin-like protein KIF13B Chains: A, B
Molecule details ›
Chains: A, B
Length: 124 amino acids
Theoretical weight: 13.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NQT8 (Residues: 440-545; Coverage: 6%)
Gene names: GAKIN, KIAA0639, KIF13B
Sequence domains:
Structure domains: Tumour Suppressor Smad4
Arf-GAP with dual PH domain-containing protein 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 392 amino acids
Theoretical weight: 45.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75689 (Residues: 1-374; Coverage: 100%)
Gene names: ADAP1, CENTA1
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand UNX 11 x UNX
Ligand ZN 2 x ZN
Ligand IP9 1 x IP9
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P41212
Unit cell:
a: 115.797Å b: 115.797Å c: 189.269Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.225 0.277
Expression system: Escherichia coli

Quick links