Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDGF receptor beta - PDGF-BB complex (preferred)
PDBe Complex ID:
PDB-CPX-134040 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Platelet-derived growth factor subunit B
Molecule details ›
Chains: A, B
Length: 172 amino acids
Theoretical weight: 19.6 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Structure domains: Cystine-knot cytokines
Length: 172 amino acids
Theoretical weight: 19.6 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P01127 (Residues: 21-185; Coverage: 75%)
Sequence domains:
Structure domains: Cystine-knot cytokines
Platelet-derived growth factor receptor beta
Molecule details ›
Chains: X, Y
Length: 289 amino acids
Theoretical weight: 32.49 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Structure domains: Immunoglobulins
Length: 289 amino acids
Theoretical weight: 32.49 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P09619 (Residues: 33-314; Coverage: 26%)
Sequence domains:
Structure domains: Immunoglobulins
