› 3mvp

X-ray diffraction
1.85Å resolution

The Crystal Structure of a TetR/AcrR transcriptional regulator from Streptococcus mutans to 1.85A

Released:
DOI: 10.2210/pdb3mvp/pdb
PDB entry 3mvp coloured by chain, front view.
PDB entry 3mvp coloured by chain, side view.
PDB entry 3mvp coloured by chain, top view.
Source organism: Streptococcus mutans UA159
Entry authors: Stein AJ, Xu X, Cui H, Chin S, Savchenko A, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184257 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 217 amino acids
Theoretical weight: 25.41 KDa
Source organism: Streptococcus mutans UA159
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8DWD0 (Residues: 1-217; Coverage: 100%)
Gene name: SMU_134
Sequence domains: Bacterial regulatory proteins, tetR family
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 50.49Å b: 80.197Å c: 110.63Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.221 0.259
Expression system: Escherichia coli BL21(DE3)

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