› 3n1b

X-ray diffraction
2.4Å resolution

C-terminal domain of Vps54 subunit of the GARP complex

Released:
DOI: 10.2210/pdb3n1b/pdb
PDB entry 3n1b coloured by chain, front view.
PDB entry 3n1b coloured by chain, side view.
PDB entry 3n1b coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex.
Pérez-Victoria FJ, Abascal-Palacios G, Tascón I, Kajava A, Magadán JG, Pioro EP, Bonifacino JS, Hierro A
Proc Natl Acad Sci U S A 107 12860-5 (2010)
PMID: 20615984

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-178271 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vacuolar protein sorting-associated protein 54 Chains: A, B
Molecule details ›
Chains: A, B
Length: 141 amino acids
Theoretical weight: 16.5 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SPW0 (Residues: 836-974; Coverage: 14%)
Gene name: Vps54
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 125.862Å b: 30.323Å c: 88.953Å
α: 90° β: 120.5° γ: 90°
R-values:
R R work R free
0.241 0.239 0.287
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Role of Rab GTPases in membrane traffic and cell physiology.
Hutagalung et al. (2011)
18 more

3 mentions without citation

Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex.
Pérez-Victoria et al. (2010)
2 more