3n1m

X-ray diffraction
1.69Å resolution

Crystal Structure of IhhN bound to BOCFn3

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-172047 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Indian hedgehog protein N-product Chain: B
Molecule details ›
Chain: B
Length: 169 amino acids
Theoretical weight: 19.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14623 (Residues: 29-193; Coverage: 43%)
Gene name: IHH
Sequence domains: Hedgehog amino-terminal signalling domain
Structure domains: Muramoyl-pentapeptide Carboxypeptidase; domain 2
Brother of CDO Chain: C
Molecule details ›
Chain: C
Length: 111 amino acids
Theoretical weight: 12.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BWV1 (Residues: 710-817; Coverage: 10%)
Gene names: BOC, UNQ604/PRO1190
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P3221
Unit cell:
a: 62.533Å b: 62.533Å c: 163.972Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.166 0.164 0.201
Expression system: Escherichia coli