› 3n8e

X-ray diffraction
2.8Å resolution

Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)

Released:
DOI: 10.2210/pdb3n8e/pdb
PDB entry 3n8e coloured by chain, front view.
PDB entry 3n8e coloured by chain, side view.
PDB entry 3n8e coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wisniewska M, Karlberg T, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson I, Kotenyova T, Moche M, Nordlund P, Nyman T, Persson C, Schutz P, Siponen MI, Svensson L, Thorsell AG, Tresaugues L, van der Berg S, Wahlberg E, Weigelt J, Welin M, Schuler H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-153700 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Stress-70 protein, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 182 amino acids
Theoretical weight: 20.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P38646 (Residues: 439-597; Coverage: 23%)
Gene names: GRP75, HSPA9, HSPA9B, mt-HSP70
Structure domains: Substrate Binding Domain Of DNAk; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P6222
Unit cell:
a: 118.68Å b: 118.68Å c: 159.87Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.208 0.206 0.242
Expression system: Escherichia coli BL21(DE3)

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