Function and Biology Details
Reaction catalysed:
Arachidonate + AH(2) + 2 O(2) = prostaglandin H(2) + A + H(2)O
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Prostaglandin G/H synthase 1 (preferred)
PDBe Complex ID:
PDB-CPX-138844 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Prostaglandin G/H synthase 1
Molecule details ›
Chains: A, B
Length: 553 amino acids
Theoretical weight: 63.72 KDa
Source organism: Ovis aries
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Animal haem peroxidase
Structure domains:
Length: 553 amino acids
Theoretical weight: 63.72 KDa
Source organism: Ovis aries
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P05979 (Residues: 32-584; Coverage: 96%)
Sequence domains: Animal haem peroxidase
Structure domains:
Ligands and Environments
Experiments and Validation Details
X-ray source:
APS BEAMLINE 5ID-B
Spacegroup:
P65
Expression system: Spodoptera frugiperda
