Function and Biology Details
Reaction catalysed:
Cleavage of Leu-|- bond in angiotensinogen to generate angiotensin I.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Renin (preferred)
PDBe Complex ID:
PDB-CPX-133566 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Renin
Molecule details ›
Chains: A, C
Length: 166 amino acids
Theoretical weight: 18.23 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains: Eukaryotic aspartyl protease
Structure domains: Acid Proteases
Length: 166 amino acids
Theoretical weight: 18.23 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical:
P00797 (Residues: 67-232; Coverage: 43%)
Sequence domains: Eukaryotic aspartyl protease
Structure domains: Acid Proteases
Renin
Molecule details ›
Chains: B, D
Length: 176 amino acids
Theoretical weight: 19.43 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains: Eukaryotic aspartyl protease
Structure domains: Acid Proteases
Length: 176 amino acids
Theoretical weight: 19.43 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical: P00797 (Residues: 237-406; Coverage: 44%)
Sequence domains: Eukaryotic aspartyl protease
Structure domains: Acid Proteases
