Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160267 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
TNFR-Cys domain-containing protein
Molecule details ›
Chain: A
Length: 163 amino acids
Theoretical weight: 18.01 KDa
Source organism: Ectromelia virus
Expression system: Escherichia coli
UniProt:
Sequence domains: Tumour necrosis factor receptor, SECRET domain
Structure domains: Viral Chemokine Inhibitor; Chain A
Length: 163 amino acids
Theoretical weight: 18.01 KDa
Source organism: Ectromelia virus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q7TDW8 (Residues: 162-320; Coverage: 50%)
Sequence domains: Tumour necrosis factor receptor, SECRET domain
Structure domains: Viral Chemokine Inhibitor; Chain A
Processed fractalkine
Molecule details ›
Chain: B
Length: 80 amino acids
Theoretical weight: 8.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Length: 80 amino acids
Theoretical weight: 8.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P78423 (Residues: 24-100; Coverage: 20%)
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRF BEAMLINE BL17U
Spacegroup:
P3221
Expression system: Escherichia coli
