› 3p1m

X-ray diffraction
2.54Å resolution

Crystal structure of human ferredoxin-1 (FDX1) in complex with iron-sulfur cluster

Released:
DOI: 10.2210/pdb3p1m/pdb
PDB entry 3p1m coloured by chain, front view.
PDB entry 3p1m coloured by chain, side view.
PDB entry 3p1m coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Chaikuad A, Johansson C, Krojer T, Yue WW, Phillips C, Bray JE, Pike ACW, Muniz JRC, Vollmar M, Weigelt J, Arrowsmith CH, Edwards AM, Bountra C, Kavanagh K, Oppermann U, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145171 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adrenodoxin, mitochondrial Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 132 amino acids
Theoretical weight: 14.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10109 (Residues: 61-184; Coverage: 67%)
Gene names: ADX, FDX1
Sequence domains: 2Fe-2S iron-sulfur cluster binding domain
Structure domains: Ubiquitin-like (UB roll)

Ligands and Environments

4 bound ligands:
Ligand FES 8 x FES
Ligand FLC 9 x FLC
Ligand K 8 x K
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P32
Unit cell:
a: 76.576Å b: 76.576Å c: 234.41Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.204 0.241
Expression system: Escherichia coli

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