› 3pgk

X-ray diffraction
2.5Å resolution

The structure of yeast phosphoglycerate kinase at 0.25 nm resolution

Released:
DOI: 10.2210/pdb3pgk/pdb
PDB entry 3pgk coloured by chain, front view.
PDB entry 3pgk coloured by chain, side view.
PDB entry 3pgk coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Sequence and structure of yeast phosphoglycerate kinase.
Watson HC, Walker NP, Shaw PJ, Bryant TN, Wendell PL, Fothergill LA, Perkins RE, Conroy SC, Dobson MJ, Tuite MF
EMBO J 1 1635-40 (1982)
PMID: 6765200

Function and Biology Details

Reaction catalysed: 
ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132718 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoglycerate kinase Chain: A
Molecule details ›
Chain: A
Length: 416 amino acids
Theoretical weight: 44.65 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
  • Canonical: P00560 (Residues: 2-259, 260-416; Coverage: 100%)
Gene names: PGK1, YCR012W, YCR12W
Sequence domains: Phosphoglycerate kinase
Structure domains: Phosphoglycerate kinase, N-terminal domain

Ligands and Environments

3 bound ligands:
Ligand MG 1 x MG
Ligand ATP 1 x ATP
Ligand 3PG 1 x 3PG
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 126.6Å b: 54.4Å c: 93Å
α: 90° β: 134.4° γ: 90°
Expression system: Not provided

Quick links

Citations

12 review citations

The P-loop--a common motif in ATP- and GTP-binding proteins.
Saraste et al. (1990)
11 more

34 mentions without citation

What lessons can be learned from studying the folding of homologous proteins?
Nickson et al. (2010)
33 more