Function and Biology Details
Reaction catalysed:
L-methionine + thioredoxin disulfide + H(2)O = L-methionine (S)-S-oxide + thioredoxin
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149801 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Thioredoxin-2
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 11.2 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin
Length: 104 amino acids
Theoretical weight: 11.2 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
- Canonical:
P22803 (Residues: 1-104; Coverage: 100%)
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin
Peptide methionine sulfoxide reductase
Molecule details ›
Chain: B
Length: 183 amino acids
Theoretical weight: 20.98 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
Sequence domains: Peptide methionine sulfoxide reductase
Structure domains: Peptide methionine sulphoxide reductase MsrA
Length: 183 amino acids
Theoretical weight: 20.98 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
- Canonical: P40029 (Residues: 2-184; Coverage: 100%)
Sequence domains: Peptide methionine sulfoxide reductase
Structure domains: Peptide methionine sulphoxide reductase MsrA
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRF BEAMLINE BL17U
Spacegroup:
I23
Expression system: Escherichia coli
