› 3pmt

X-ray diffraction
1.8Å resolution

Crystal structure of the Tudor domain of human Tudor domain-containing protein 3

Released:
DOI: 10.2210/pdb3pmt/pdb
PDB entry 3pmt coloured by chain, front view.
PDB entry 3pmt coloured by chain, side view.
PDB entry 3pmt coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30.
Liu K, Guo Y, Liu H, Bian C, Lam R, Liu Y, Mackenzie F, Rojas LA, Reinberg D, Bedford MT, Xu RM, Min J
PLoS One 7 e30375 (2012)
PMID: 22363433

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190662 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tudor domain-containing protein 3 Chain: A
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H7E2 (Residues: 553-611; Coverage: 9%)
Gene name: TDRD3
Sequence domains: Tudor domain
Structure domains: SH3 type barrels.

Ligands and Environments

1 bound ligand:
Ligand PG4 1 x PG4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P65
Unit cell:
a: 41.682Å b: 41.682Å c: 59.947Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.179 0.178 0.209
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

17 review citations

Protein arginine methyltransferases and cancer.
Yang et al. (2013)
16 more

4 mentions without citation

What's all the phos about? Insights into the phosphorylation state of the RNA polymerase II C-terminal domain via mass spectrometry.
LeBlanc et al. (2021)
3 more