› 3pn7

X-ray diffraction
2.25Å resolution

Visualizing new hinges and a potential major source of compliance in the lever arm of myosin

Released:
DOI: 10.2210/pdb3pn7/pdb
PDB entry 3pn7 coloured by chain, front view.
PDB entry 3pn7 coloured by chain, side view.
PDB entry 3pn7 coloured by chain, top view.
Source organism: Placopecten magellanicus
Primary publication:
Visualizing key hinges and a potential major source of compliance in the lever arm of myosin.
Brown JH, Kumar VS, O'Neall-Hennessey E, Reshetnikova L, Robinson H, Nguyen-McCarty M, Szent-Györgyi AG, Cohen C
Proc Natl Acad Sci U S A 108 114-9 (2011)
PMID: 21149681

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173239 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Myosin heavy chain Chains: A, D
Molecule details ›
Chains: A, D
Length: 69 amino acids
Theoretical weight: 8.6 KDa
Source organism: Placopecten magellanicus
UniProt:
  • Canonical: Q26080 (Residues: 771-839; Coverage: 4%)
Structure domains: Myosin, subunit A
EF-hand domain-containing protein Chains: B, E
Molecule details ›
Chains: B, E
Length: 161 amino acids
Theoretical weight: 18.4 KDa
Source organism: Placopecten magellanicus
UniProt:
  • Canonical: Q26069 (Residues: 2-162; Coverage: 99%)
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
EF-hand domain-containing protein Chains: C, F
Molecule details ›
Chains: C, F
Length: 156 amino acids
Theoretical weight: 17.68 KDa
Source organism: Placopecten magellanicus
UniProt:
  • Canonical: Q26066 (Residues: 2-157; Coverage: 99%)
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

2 bound ligands:
Ligand MG 2 x MG
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P1
Unit cell:
a: 50.737Å b: 68.779Å c: 79.305Å
α: 77.41° β: 85.94° γ: 73.61°
R-values:
R R work R free
0.191 0.191 0.241

Quick links

Citations

5 review citations

Myosin light chains: Teaching old dogs new tricks.
Heissler et al. (2014)
4 more

4 mentions without citation

Visualizing key hinges and a potential major source of compliance in the lever arm of myosin.
Brown et al. (2011)
3 more