Function and Biology Details
Reaction catalysed:
NADPH + n oxidized hemoprotein = NADP(+) + n reduced hemoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Flavoprotein pyridine nucleotide cytochrome reductase
- Flavodoxin-like
- Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
- Flavodoxin/nitric oxide synthase
- Flavoprotein-like superfamily
- NADPH-cytochrome P450 reductase
- Oxidoreductase FAD/NAD(P)-binding
- NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily
3 more domains
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
NADPH--cytochrome P450 reductase (preferred)
PDBe Complex ID:
PDB-CPX-147724 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NADPH--cytochrome P450 reductase
Molecule details ›
Chains: A, B
Length: 618 amino acids
Theoretical weight: 70.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 618 amino acids
Theoretical weight: 70.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P16435 (Residues: 64-677; Coverage: 91%)
Sequence domains:
Structure domains:
