› 3qqn

X-ray diffraction
2.31Å resolution

The retinal specific CD147 Ig0 domain: from molecular structure to biological activity

Released:
DOI: 10.2210/pdb3qqn/pdb
PDB entry 3qqn coloured by chain, front view.
PDB entry 3qqn coloured by chain, side view.
PDB entry 3qqn coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The retinal specific CD147 Ig0 domain: from molecular structure to biological activity.
Redzic JS, Armstrong GS, Isern NG, Jones DN, Kieft JS, Eisenmesser EZ
J Mol Biol 411 68-82 (2011)
PMID: 21620857

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152971 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Basigin Chains: A, B
Molecule details ›
Chains: A, B
Length: 137 amino acids
Theoretical weight: 15.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P35613 (Residues: 23-138; Coverage: 32%)
Gene names: BSG, UNQ6505/PRO21383
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P6522
Unit cell:
a: 80.24Å b: 80.24Å c: 160.67Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.238 0.234 0.269
Expression system: Escherichia coli

Quick links

Citations

10 review citations

The biological function and clinical utilization of CD147 in human diseases: a review of the current scientific literature.
Xiong et al. (2014)
9 more

4 mentions without citation

Vaccine-induced immune thrombotic thrombocytopenia after vaccination against Covid-19: A clinical dilemma for clinicians and patients.
Mohseni Afshar et al. (2022)
3 more