› 3qvn

X-ray diffraction
2.6Å resolution

Crystal Structure of cytosolic MnSOD3 from Candida albicans

Released:
DOI: 10.2210/pdb3qvn/pdb
PDB entry 3qvn coloured by chain, front view.
PDB entry 3qvn coloured by chain, side view.
PDB entry 3qvn coloured by chain, top view.
Source organism: Candida albicans
Primary publication:
Comparison of two yeast MnSODs: mitochondrial Saccharomyces cerevisiae versus cytosolic Candida albicans.
Sheng Y, Stich TA, Barnese K, Gralla EB, Cascio D, Britt RD, Cabelli DE, Valentine JS
J Am Chem Soc 133 20878-89 (2011)
PMID: 22077216

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188774 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase Chain: A
Molecule details ›
Chain: A
Length: 206 amino acids
Theoretical weight: 22.76 KDa
Source organism: Candida albicans
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q96UT6 (Residues: 1-206; Coverage: 100%)
Gene names: CaJ7.0018, FOB64_003536, SOD2, Sod3
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand MN 1 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P6422
Unit cell:
a: 77.134Å b: 77.134Å c: 120.08Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.214 0.212 0.273
Expression system: Saccharomyces cerevisiae

Quick links

Citations

4 review citations

Superoxide dismutases and superoxide reductases.
Sheng et al. (2014)
3 more

2 mentions without citation

Comparison of two yeast MnSODs: mitochondrial Saccharomyces cerevisiae versus cytosolic Candida albicans.
Sheng et al. (2011)
1 more