› 3r3m

X-ray diffraction
3Å resolution

Crystal structure of the FAF1 UBX domain

Released:
DOI: 10.2210/pdb3r3m/pdb
PDB entry 3r3m coloured by chain, front view.
PDB entry 3r3m coloured by chain, side view.
PDB entry 3r3m coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Hierarchical binding of cofactors to the AAA ATPase p97.
Hänzelmann P, Buchberger A, Schindelin H
Structure 19 833-43 (2011)
PMID: 21645854

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193999 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
FAS-associated factor 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 85 amino acids
Theoretical weight: 9.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UNN5 (Residues: 568-650; Coverage: 13%)
Gene names: CGI-03, FAF1, UBXD12, UBXN3A
Sequence domains: UBX domain
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:
Ligand PO4 3 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P61
Unit cell:
a: 92.755Å b: 92.755Å c: 108.5Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.174 0.258
Expression system: Escherichia coli

Quick links

Citations

17 review citations

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system.
Meyer et al. (2012)
16 more