Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-127157 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Vesicle-associated membrane protein 2
Molecule details ›
Chains: A, E, I, M, Q, U, Y, c
Length: 37 amino acids
Theoretical weight: 4.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Synaptobrevin
Length: 37 amino acids
Theoretical weight: 4.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P63027 (Residues: 28-60; Coverage: 28%)
Sequence domains: Synaptobrevin
Syntaxin-1A
Molecule details ›
Chains: B, F, J, N, R, V, Z, d
Length: 65 amino acids
Theoretical weight: 7.55 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
Sequence domains: SNARE domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 65 amino acids
Theoretical weight: 7.55 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
- Canonical: P32851 (Residues: 191-253; Coverage: 22%)
Sequence domains: SNARE domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Synaptosomal-associated protein 25
Molecule details ›
Chains: C, G, K, O, S, W, a, e
Length: 81 amino acids
Theoretical weight: 9.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 81 amino acids
Theoretical weight: 9.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P60880 (Residues: 7-82; Coverage: 37%)
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Synaptosomal-associated protein 25
Molecule details ›
Chains: D, H, L, P, T, X, b, f
Length: 65 amino acids
Theoretical weight: 7.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 65 amino acids
Theoretical weight: 7.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P60880 (Residues: 141-203; Coverage: 31%)
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Complexin-1
Molecule details ›
Chains: g, h, i, j, k, l, m, n
Length: 63 amino acids
Theoretical weight: 7.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Synaphin protein
Structure domains: Single Helix bin
Length: 63 amino acids
Theoretical weight: 7.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O14810 (Residues: 26-83; Coverage: 43%)
Sequence domains: Synaphin protein
Structure domains: Single Helix bin
