› 3rrq

X-ray diffraction
2.1Å resolution

Crystal structure of the extracellular domain of human PD-1

Released:
DOI: 10.2210/pdb3rrq/pdb
PDB entry 3rrq coloured by chain, front view.
PDB entry 3rrq coloured by chain, side view.
PDB entry 3rrq coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lazar-Molnar E, Ramagopal UA, Nathenson SG, Almo SC

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172197 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Programmed cell death protein 1 Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15116 (Residues: 32-160; Coverage: 49%)
Gene names: PD1, PDCD1
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P6522
Unit cell:
a: 46.02Å b: 46.02Å c: 187.395Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.214 0.249
Expression system: Escherichia coli BL21(DE3)

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