› 3s5p

X-ray diffraction
2.3Å resolution

Crystal structure of ribose-5-phosphate isomerase B RpiB from Giardia lamblia

Released:
DOI: 10.2210/pdb3s5p/pdb
PDB entry 3s5p coloured by chain, front view.
PDB entry 3s5p coloured by chain, side view.
PDB entry 3s5p coloured by chain, top view.
Source organism: Giardia lamblia ATCC 50803
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
D-ribose 5-phosphate = D-ribulose 5-phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-108571 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribose 5-phosphate isomerase Chains: A, B
Molecule details ›
Chains: A, B
Length: 166 amino acids
Theoretical weight: 17.66 KDa
Source organism: Giardia lamblia ATCC 50803
Expression system: Escherichia coli
UniProt:
  • Canonical: A8B2K2 (Residues: 1-145; Coverage: 100%)
Gene names: GL50803_0027614, GL50803_27614
Sequence domains: Ribose/Galactose Isomerase
Structure domains: Sugar-phosphate isomerase, RpiB/LacA/LacB

Ligands and Environments

1 bound ligand:
Ligand SO4 5 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P3121
Unit cell:
a: 89.2Å b: 89.2Å c: 68.24Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.198 0.234
Expression system: Escherichia coli

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