3s9d

X-ray diffraction
2Å resolution

binary complex between IFNa2 and IFNAR2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-134393 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interferon alpha-2 Chains: A, C
Molecule details ›
Chains: A, C
Length: 168 amino acids
Theoretical weight: 19.39 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P01563 (Residues: 24-188; Coverage: 100%)
Gene names: IFNA2, IFNA2A, IFNA2B, IFNA2C
Sequence domains: Interferon alpha/beta domain
Structure domains: Growth Hormone; Chain: A;
Interferon alpha/beta receptor 2 Chains: B, D
Molecule details ›
Chains: B, D
Length: 199 amino acids
Theoretical weight: 22.8 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P48551 (Residues: 37-232; Coverage: 40%)
Gene names: IFNABR, IFNAR2, IFNARB
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P21
Unit cell:
a: 84.65Å b: 62.01Å c: 88.08Å
α: 90° β: 92.68° γ: 90°
R-values:
R R work R free
0.204 0.204 0.233
Expression system: Trichoplusia ni