› 3soa

X-ray diffraction
3.55Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194071 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase type II subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 444 amino acids
Theoretical weight: 50.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UQM7 (Residues: 1-474; Coverage: 93%)
Gene names: CAMK2A, CAMKA, KIAA0968
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand DB8 1 x DB8
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P622
Unit cell:
a: 155.72Å b: 155.72Å c: 106.16Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.278 0.273 0.327
Expression system: Escherichia coli

Quick links

Citations

42 review citations

Mechanisms of CaMKII action in long-term potentiation.
Lisman et al. (2012)
41 more

37 mentions without citation

CaMKII regulation in information processing and storage.
Coultrap et al. (2012)
36 more