› 3soo

X-ray diffraction
2.73Å resolution

Crystal structure of a LINE-1 type transposase domain-containing protein 1 (L1TD1) from HOMO SAPIENS at 2.73 A resolution

Released:
DOI: 10.2210/pdb3soo/pdb
PDB entry 3soo coloured by chain, front view.
PDB entry 3soo coloured by chain, side view.
PDB entry 3soo coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178308 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
LINE-1 type transposase domain-containing protein 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 88 amino acids
Theoretical weight: 10.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5T7N2 (Residues: 235-321; Coverage: 10%)
Gene names: ECAT11, L1TD1
Sequence domains: L1 transposable element dsRBD-like domain
Structure domains: L1 transposable element, C-terminal domain

Ligands and Environments

2 bound ligands:
Ligand SO4 8 x SO4
Ligand CL 1 x CL
2 modified residues:
Ligand MSE 6 x MSE
Ligand MLY 30 x MLY

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P6522
Unit cell:
a: 69.14Å b: 69.14Å c: 292.27Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.228 0.226 0.259
Expression system: Escherichia coli

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