› 3sqj

X-ray diffraction
2.05Å resolution

Recombinant human serum albumin from transgenic plant

Released:
DOI: 10.2210/pdb3sqj/pdb
PDB entry 3sqj coloured by chain, front view.
PDB entry 3sqj coloured by chain, side view.
PDB entry 3sqj coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Large-scale production of functional human serum albumin from transgenic rice seeds.
He Y, Ning T, Xie T, Qiu Q, Zhang L, Sun Y, Jiang D, Fu K, Yin F, Zhang W, Shen L, Wang H, Li J, Lin Q, Sun Y, Li H, Zhu Y, Yang D
Proc Natl Acad Sci U S A 108 19078-83 (2011)
PMID: 22042856

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136176 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Albumin Chains: A, B
Molecule details ›
Chains: A, B
Length: 582 amino acids
Theoretical weight: 66.27 KDa
Source organism: Homo sapiens
Expression system: Oryza sativa
UniProt:
  • Canonical: P02768 (Residues: 27-608; Coverage: 99%)
Gene names: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
Sequence domains: Serum albumin family
Structure domains: Serum Albumin; Chain A, Domain 1

Ligands and Environments

1 bound ligand:
Ligand MYR 15 x MYR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21
Unit cell:
a: 95.61Å b: 38.368Å c: 184.037Å
α: 90° β: 104.93° γ: 90°
R-values:
R R work R free
0.238 0.235 0.303
Expression system: Oryza sativa

Quick links

Citations

25 review citations

The thiol pool in human plasma: the central contribution of albumin to redox processes.
Turell et al. (2013)
24 more

4 mentions without citation

Large-scale production of functional human serum albumin from transgenic rice seeds.
He et al. (2011)
3 more