› 3tb5

X-ray diffraction
2.3Å resolution

Crystal Structure of the Enterococcus faecalis Methionine aminopeptidase apo form

Released:
DOI: 10.2210/pdb3tb5/pdb
PDB entry 3tb5 coloured by chain, front view.
PDB entry 3tb5 coloured by chain, side view.
PDB entry 3tb5 coloured by chain, top view.
Source organism: Enterococcus faecalis HIP11704
Primary publication:
Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2'-bipyridine based inhibitors
Kishor C, Gumpena R, Reddi R, Addlagatta A
MEDCHEMCOMM 3 1406-1412 (2012)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164070 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Methionine aminopeptidase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 264 amino acids
Theoretical weight: 29.45 KDa
Source organism: Enterococcus faecalis HIP11704
Expression system: Escherichia coli
Structure domains: Creatinase/methionine aminopeptidase superfamily

Ligands and Environments

1 bound ligand:
Ligand CIT 2 x CIT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: C2
Unit cell:
a: 120.74Å b: 132.13Å c: 85.3Å
α: 90° β: 133.36° γ: 90°
R-values:
R R work R free
0.2 0.197 0.255
Expression system: Escherichia coli

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