› 3tbd

X-ray diffraction
1.8Å resolution

Crystal Structure of domain VI and LE1 of human Netrin-G2

Released:
DOI: 10.2210/pdb3tbd/pdb
PDB entry 3tbd coloured by chain, front view.
PDB entry 3tbd coloured by chain, side view.
PDB entry 3tbd coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the ligand binding domain of netrin G2.
Brasch J, Harrison OJ, Ahlsen G, Liu Q, Shapiro L
J Mol Biol 414 723-34 (2011)
PMID: 22041449

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188424 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Netrin-G2 Chain: A
Molecule details ›
Chain: A
Length: 338 amino acids
Theoretical weight: 38.98 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q96CW9 (Residues: 18-349; Coverage: 65%)
Gene names: KIAA1857, LMNT2, NTNG2, UNQ9381/PRO34206
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
3 bound ligands:
Ligand CA 1 x CA
Ligand PO4 2 x PO4
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P3221
Unit cell:
a: 63.134Å b: 63.134Å c: 190.64Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.175 0.227
Expression system: Homo sapiens

Quick links

Citations

4 review citations

Laminins in basement membrane assembly.
Hohenester et al. (2013)
3 more

6 mentions without citation

Structures from anomalous diffraction of native biological macromolecules.
Liu et al. (2012)
5 more