Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156541 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit alpha-5, N-terminally processed
Molecule details ›
Chains: A, B
Length: 447 amino acids
Theoretical weight: 49.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 447 amino acids
Theoretical weight: 49.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P52294 (Residues: 66-512; Coverage: 83%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Nuclear pore complex protein Nup50
Molecule details ›
Chains: C, D
Length: 114 amino acids
Theoretical weight: 11.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: NUP50 (Nucleoporin 50 kDa)
Length: 114 amino acids
Theoretical weight: 11.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9UKX7 (Residues: 1-109; Coverage: 23%)
Sequence domains: NUP50 (Nucleoporin 50 kDa)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X6A, NSLS BEAMLINE X25
Spacegroup:
P212121
Expression system: Escherichia coli
