› 3u5v

X-ray diffraction
1.7Å resolution

Crystal structure of Max-E47

Released:
DOI: 10.2210/pdb3u5v/pdb
PDB entry 3u5v coloured by chain, front view.
PDB entry 3u5v coloured by chain, side view.
PDB entry 3u5v coloured by chain, top view.
Source organisms:
Primary publication:
Crystal structure of the minimalist Max-E47 protein chimera.
Ahmadpour F, Ghirlando R, De Jong AT, Gloyd M, Shin JA, Guarné A
PLoS One 7 e32136 (2012)
PMID: 22389683

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147535 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein max; Transcription factor E2-alpha Chain: A
Molecule details ›
Chain: A
Length: 76 amino acids
Theoretical weight: 9.08 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P28574 (Residues: 22-36, 58-58; Coverage: 10%)
  • Canonical: P15923 (Residues: 563-584, 586-613; Coverage: 8%)
Gene names: BHLHB21, E2A, ITF1, Max, Myn, TCF3
Sequence domains: Helix-loop-helix DNA-binding domain
Structure domains: Helix-loop-helix DNA-binding domain

Ligands and Environments

1 bound ligand:
Ligand NO3 2 x NO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: I212121
Unit cell:
a: 37.48Å b: 49.466Å c: 74.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.207 0.235
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc.
Madden et al. (2021)
1 more

1 mention without citation

Crystal structure of the minimalist Max-E47 protein chimera.
Ahmadpour et al. (2012)