› 3uf1

X-ray diffraction
2.81Å resolution

Crystal Structure of Vimentin (fragment 144-251) from Homo sapiens, Northeast Structural Genomics Consortium Target HR4796B

Released:
DOI: 10.2210/pdb3uf1/pdb
PDB entry 3uf1 coloured by chain, front view.
PDB entry 3uf1 coloured by chain, side view.
PDB entry 3uf1 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography.
Aziz A, Hess JF, Budamagunta MS, Voss JC, Kuzin AP, Huang YJ, Xiao R, Montelione GT, FitzGerald PG, Hunt JF
J Biol Chem 287 28349-61 (2012)
PMID: 22740688

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140284 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vimentin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 119 amino acids
Theoretical weight: 14.64 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P08670 (Residues: 144-251; Coverage: 23%)
Gene name: VIM
Sequence domains: Intermediate filament protein

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 20 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P212121
Unit cell:
a: 61.017Å b: 86.81Å c: 114.927Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.239 0.234 0.284
Expression system: Not provided

Quick links

Citations

7 review citations

Intermediate Filaments: Structure and Assembly.
Herrmann et al. (2016)
6 more

20 mentions without citation

Recent insight into intermediate filament structure.
Eldirany et al. (2021)
19 more