› 3ulh

X-ray diffraction
2.54Å resolution

Crystal structure of a RNA binding domain of THO complex subunit 4 protein (THOC4) from Homo sapiens at 2.54 A resolution

Released:
DOI: 10.2210/pdb3ulh/pdb
PDB entry 3ulh coloured by chain, front view.
PDB entry 3ulh coloured by chain, side view.
PDB entry 3ulh coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183208 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
THO complex subunit 4 Chain: A
Molecule details ›
Chain: A
Length: 107 amino acids
Theoretical weight: 11.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q86V81 (Residues: 78-183; Coverage: 41%)
Gene names: ALY, ALYREF, BEF, THOC4
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

1 bound ligand:
Ligand PO4 2 x PO4
1 modified residue:
Ligand MSE 2 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P4132
Unit cell:
a: 101.152Å b: 101.152Å c: 101.152Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.181 0.195
Expression system: Escherichia coli

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